Research Area A: Molecular basis of selective autophagy |
A01 | Structural investigation of the interaction of domains involved in autophagy and their regulation by post-translational modifications | Volker Dötsch & Stefan Knapp |
A02 | Systemic analysis of autophagy degradome | Christian Behrends |
A03 | BAG3-mediated selective macroautophagy and its modulation | Christian Behl |
A04 | Regulatory interplay between autophagosomal and endosomal pathways | Ivan Dikic |
A05 | Regulation of autophagy by deubiquitylating enzymes | Anja Bremm |
Research Area B: Functional characterization of selective autophagy |
B01 | Autophagy in ribosome biogenesis and quality control | Stefan Müller |
B02 | Autophagy in the cellular response to genotoxic stress | Petra Beli |
B03 | Evolution of autophagy and role in aging and development | Heinz D. Osiewacz |
B04 | Crosstalk between autophagy, apoptosis, and mitochondrial dynamics during development and tumorigenesis | Christian Pohl |
B05 | Protein engineering of sensors and modulators of autophagy | Andreas Ernst |
B06 | Mitophagy induction by the mitochondrial unfolded protein response | Münch Christian |
Research Area C: Selective autophagy in human disease models |
C01 | Autophagy as a host defense mechanism against bacterial infections | Ivan Dikic |
C02 | Regulation of autophagy in pathogen-induced and sterile inflammation | Liliana Schaefer |
C03 | Crosstalk of autophagy and inflammatory signaling pathways during acute intestinal inflammation | Florian Greten |
C05 | The selective autophagy receptors p62 and CBL in normal and malignant hematopoiesis | Christian Brandts |
C06 | Deciphering the role of autophagy in activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL) | Thomas Oellerich & Hubert Serve |
C07 | Molecular targeting of autophagy in glioblastoma | Simone Fulda & Donat Kögel |
Scientific service project |
Z01 | Quantitative autophagy proteomics platform | Christian Behrends & Petra Beli |